Valencia were stunned by struggling Numancia while Deportivo La Coruna rose to sixth after triumphing in an eight-goal thriller in Primera Division on Sunday.
Numancia headed into their encounter against stuttering Valencia aiming to halt a run of seven straight league losses.
Rojillos were dealt a blow after just nine minutes when Vicente broke the deadlock, but Carlos Aranda restored parity before the interval.
Jose Barkero then left Los Che shell-shocked as he netted the winner for Numancia to lift the club off the foot of the table.
Deportivo climbed to within three points of fourth-placed Villarreal with a thrilling 5-3 triumph over out-of-form Racing Santander.
Jonathan handed Racing the lead after just one minute but Juan Rodriguez equalised for Depor on 25 minutes.
Towering striker Nikola Zigic then restored Racing's advantage before a brace from substitute Riki sandwiched a strike from Angel Lafita to hand Depor the edge.
Joan Verdu bagged a fifth for the home side before Jesus Berrocal came off the bench for Racing to net a consolation.
Malaga rose to fifth with a 2-1 triumph over Getafe, in a game where both sides ended the 90 minutes with 10 men.
Pereira Eliseu and Nabil Baha put Malaga 2-0 up before Ivan Javier Cuadra received two yellow cards.
Getafe substitute Cosmin Contra pulled a goal back for the home side but a comeback was not to be as Roberto Soldado received his marching orders late on.
Real Mallorca came from a remarkable three goals down to secure a point against fellow strugglers Real Betis.
Goals from Mark Gonzalez, Sergio Garcia and Arturo Arzu handed Betis a resounding lead, with Mallorca seemingly dead and buried.
However, substitutes Gonzalo Castro and Pierre Webo pulled two back for Mallorca before a second from Castro salvaged a dramatic draw.
Real Valladolid disposed of Recreativo Huelva 3-2 in a heated game at Estadio Nuevo Colombino.
Goals from Sesma Jonathan and Nenok Goitom put Valladolid ahead before Perez Adrian Colunga pulled one back for Recreativo from the penalty spot.
Goitom netted his second of the game after the break but a hat-trick was not to be after he was handed his marching orders.
Recreativo then set up a nervy finish for Valladolid as Javier Camunas made it 3-2, but a comeback did not ensue, despite Rubio Alvaro also being dismissed in the latter stages.
Sevilla tightened their grip on third as they defeated mid-table Almeria 2-1 at the Estadio Ramon Sanchez Pizjuan.
Former West Ham and Tottenham striker Frederic Kanoute opened the scoring after just five minutes, before Renato doubled their advantage in the second period.
Alvaro Negredo reduced arrears from the penalty spot in the 71st minute, but it was too little, too late for the away side.
Osasuna remain in the relegation places after they were defeated 2-1 at home by Sporting Gijon.
Torres David Barral and Gimenez Diego Castro were both on target for Sporting Gijon, while Osasuna could only muster a consolation through Javad Nekounam.
